Download Antitumor Steroids by R T Blickenstaff PDF

By R T Blickenstaff

Antitumor Steroids examines using steroids, in addition to nonsteroidal antiestrogens and a few benzo[a]carbazoles, within the therapy of melanoma. It explains the mechanism during which steroids and their receptors interact to impact their physiological capabilities ordinarily and their antitumor job particularly. It additionally describes the systematic screening of antitumor compounds remoted from traditional resources.
Organized into 9 chapters, this e-book starts off with an summary of the position of steroids in melanoma remedy. It then discusses the estrogens, antiestrogens, and compounds (all containing an fragrant A-ring). the following chapters think of androgens, a few antiandrogens, derivatives in accordance with C-19 steroids, progestins and corticoids, bile acids, and compounds with a side-chain carboxyl workforce. The e-book explains the biogenesis and metabolism of androgens; the pharmacology of medroxyprogesterone acetate; the antitumor homes of certainly happening corticosteroids; sterols and cucurbitacins; diet D and its metabolites; and cardenolides, bufadienolides, and withanolides. The publication concludes with a bankruptcy on bile acids, sapogenins and its analogs, and miscellaneous steroids.
This ebook is a beneficial source for natural and medicinal chemists biochemists, and pharmacologists drawn to using steroids in treating cancer.

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